Preperitoneal well-differentiated liposarcoma. Case Report
DOI:
https://doi.org/10.47464/MetroCiencia/vol32/2/2024/50-56Keywords:
atypical lipomatous tumor, liposarcoma, well-differentiated liposarcoma, Well-differentiated liposarcoma of preperitoneal fatAbstract
Liposarcoma is a rare type of mesenchymal tumor that accounts for less than 1% of all malignant neoplasms. Among these, well-differentiated liposarcoma, also known as atypical lipomatous tumor, is the most common, representing 40-45% of liposarcomas. Its risk factors are still unknown, and due to its low incidence rate, diagnostic and treatment options are limited. It is most reported in the extremities and retroperitoneum, but there are no reports of incidence in the preperitoneal fat. Therefore, there is interest in reporting a case of a 51-year-old woman with a slowly growing abdominal mass who underwent laparotomy, revealing a large preperitoneal mass, which was later histopathological confirmed as well-differentiated liposarcoma. The treatment of choice for these tumors is complete resection with negative margins and regular follow-up, as they often carry risks of recurrence. The efficacy of radiotherapy in managing these tumors is still debatable.
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Rosas Marroquín N, Mejía Rodriguez UP, Saravia Romaní L, Molina Serrano Y. Liposarcoma de alto grado con áreas de necrosis hemorragica. Reporte de un caso en el Hospital Central de la Fuerza Aérea del Perú. Revista Médica Basadrina. 2019 May 8;10(1):45–9.
Hogg ME, Wayne JD. Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma: What Is It? Surg Oncol Clin N Am [Internet]. 2012 Apr 1 [cited 2023 Nov 16];21(2):333–40. Available from: http://www.surgonc.theclinics.com/article/S1055320711001128/fulltext
Bagaria SP, Gabriel E, Mann GN. Multiply recurrent retroperitoneal liposarcoma. J Surg Oncol. 2018 Jan 19;117(1):62–8.
Laurino L, Furlanetto A, Orvieto E, Dei Tos AP. Well-differentiated liposarcoma (atypical lipomatous tumors). Semin Diagn Pathol. 2001 Nov;18(4):258–62.
Dei Tos AP. Liposarcoma: New entities and evolving concepts. Ann Diagn Pathol. 2000 Aug 1;4(4):252–66.
Evans HL. Atypical lipomatous tumor, its variants, and its combined forms: a study of 61 cases, with a minimum follow-up of 10 years. Am J Surg Pathol [Internet]. 2007 Jan [cited 2023 Nov 15];31(1):1–14. Available from: https://pubmed.ncbi.nlm.nih.gov/17197914/
Karadayi K, Yildiz C, Karakus S, Kurt A, Bozkurt B, Soylu S, et al. Well-differentiated abdominal liposarcoma: experience of a tertiary care center. World J Surg Oncol. 2015 Dec 1;13(1):166.
Kooby DACB. Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: Importance of histological subtype with treatment recommendations. Ann Surg Oncol. 2003;78–84.
Ramírez Pedroza LV, Mantilla Viviescas KA, Lubinus Badillo FG. Liposarcoma pleomórfico, reporte de caso. MedUNAB. 2017 Aug 3;19(3):230–4.
Dalal KM, Antonescu CR, Singer S. Diagnosis and management of lipomatous tumors. J Surg Oncol. 2008 Mar 15;97(4):298–313.
Thway K. Well-differentiated liposarcoma and dedifferentiated liposarcoma: An updated review. Semin Diagn Pathol. 2019 Mar;36(2):112–21.
Asano Y, Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, et al. A scoring system combining clinical, radiological, and histopathological examinations for differential diagnosis between lipoma and atypical lipomatous tumor/well-differentiated liposarcoma. Sci Rep. 2022 Jan 7;12(1):237.
Sandoval Rodríguez JI, Serrano Quintero LN, Granillo Cendón I, Morales Palomares MÁ. Liposarcoma retroperitoneal gigante: reporte de caso y revisión de la literatura. Revista Chilena de Cirugía. 2016 Nov;68(6):449–52.
Lee ATJ, Thway K, Huang PH, Jones RL. Clinical and Molecular Spectrum of Liposarcoma. Journal of Clinical Oncology. 2018 Jan 10;36(2):151–9.
Choi KY, Jost E, Mack L, Bouchard-Fortier A. Surgical management of truncal and extremities atypical lipomatous tumors/well-differentiated liposarcoma: A systematic review of the literature. The American Journal of Surgery. 2020 May;219(5):823–7.
Leiting JL, Bergquist JR, Hernandez MC, Merrell KW, Folpe AL, Robinson SI, et al. Radiation Therapy for Retroperitoneal Sarcomas: Influences of Histology, Grade, and Size. Sarcoma. 2018 Dec 5;2018:1–8.
Colomo R, Lagos M, Aragón G. Liposarcoma retroperitoneal gigante: informe de un caso. Sociedad Andaluza de patología digestiva. 2018;50–2.
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Copyright (c) 2024 Alexis Haro Perdomo, José Antonio Darquea Molina, Jorge Augusto Torres Ruales, Gabriela Soraya Calderon Pasquel
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